Description

What is Methallylescaline (MAL)?

Methallylescaline (MAL) is a synthetic psychedelic phenethylamine belonging to the mescaline family. It is a psychoactive substance known for producing hallucinations, altered perceptions, and changes in consciousness. Methallylescaline is structurally similar to mescaline, a naturally occurring compound found in certain cacti like peyote and San Pedro, but with added chemical modifications that influence its potency and effects.

Chemical Structure

IUPAC Name: 2-(4-methoxy-3,5-dimethoxyphenyl)-N-methallylethanamine
Chemical Formula: $C_{13}H_{19}NO_3$
Class: Phenethylamine derivative
Related Compounds:
- Mescaline
- Allylescaline
- Proscaline

The primary difference between methallylescaline and mescaline lies in its N-substitution with a methallyl group. This alteration affects its binding affinity to serotonin receptors, potentially increasing its potency compared to mescaline.

Mechanism of Action

Methallylescaline acts primarily on serotonin receptors (5-HT2A) in the brain, which are responsible for its hallucinogenic effects. Similar to other psychedelics, it stimulates activity in these receptors, leading to changes in sensory perception, emotional state, and cognition.

Effects

Methallylescaline is a potent hallucinogen with effects comparable to mescaline, though with slight differences due to its chemical modifications.

Physical Effects:

Stimulation and increased energy
Nausea (common with phenethylamines)
Increased heart rate and body temperature
Mild physical discomfort or restlessness in some users

Cognitive Effects:

Enhanced introspection
Altered thought patterns and perspective shifts
Feelings of euphoria or profound insight

Perceptual Effects:

Visual hallucinations (e.g., geometric patterns, color enhancement)
Auditory distortions
Altered sense of time and space

Duration:

Onset: 30–90 minutes
Peak: 2–4 hours
Total Duration: 8–12 hours

Dosage

Because methallylescaline is a research chemical, dosing recommendations are not standardized. Most users report effective doses in the range of 40–80 mg. The effects are dose-dependent, with higher doses leading to more intense psychedelic experiences but also increased risk of adverse effects.

Safety and Risks

Adverse Effects:

Anxiety or paranoia, especially at higher doses
Nausea and gastrointestinal discomfort
Elevated heart rate and blood pressure
Risk of overstimulation or “bad trips”

Toxicity:

Little is known about the toxicity or long-term effects of methallylescaline.
Overdose potential is not well-documented but could lead to serious side effects.

Harm Reduction:

Start with a low dose if using for the first time.
Avoid combining with other substances, especially stimulants or depressants.
Use in a safe, controlled environment with a trusted sitter if necessary.

Legality

Methallylescaline is classified as a research chemical, and its legal status varies globally:

USA: Likely falls under the Federal Analogue Act, meaning it could be treated as illegal if intended for human consumption.
Europe: Many countries consider it a controlled substance or have analog laws that apply.
Elsewhere: Often exists in a legal gray area due to its niche nature.

Comparison to Related Compounds

Compound	Duration	Effects	Potency
Mescaline	10–12 hours	Traditional, gentle psychedelic	Less potent
Methallylescaline	8–12 hours	Stimulating and introspective	Moderate potency
Allylescaline	6–10 hours	Euphoria and mild hallucinations	Similar potency

Research Status

Methallylescaline has limited scientific research due to its classification as a designer drug. Most knowledge comes from anecdotal reports and user experiences. Research on its effects, safety profile, and long-term risks is minimal, making it important to approach with caution.

Key Characteristics of Methallylescaline Hydrochloride:

Chemical Structure:
- Methallylescaline is a 3,4,5-trimethoxyphenethylamine derivative, meaning it has three methoxy groups attached to the benzene ring at positions 3, 4, and 5. The distinguishing feature is the methallyl group attached to the nitrogen atom.
- This structural alteration makes methallylescaline different from mescaline, although both substances share a similar psychedelic profile.
Effects:
- Psychedelic Experience: Methallylescaline produces hallucinogenic effects similar to other phenethylamines. These can include visual distortions, geometric patterns, and an altered perception of reality.
- Euphoria: Users often report feeling euphoric, happy, and content.
- Cognitive Alteration: Methallylescaline can lead to changes in thought patterns, introspection, and a heightened sense of creativity.
- Sensory Enhancement: It enhances sensory experiences, making colors appear more vibrant and sounds more vivid.
- Body High: Users sometimes describe a mild to moderate body high, with sensations of lightness or energy.
Dosage:
- The typical oral dose of methallylescaline hydrochloride is usually around 20 to 80 mg. The effects are dose-dependent, with lower doses producing milder psychedelic effects, and higher doses inducing stronger visuals and altered cognition.
Duration:
- Methallylescaline has a relatively long duration of action compared to other psychedelics. Effects typically begin 30 to 90 minutes after ingestion and can last between 8 to 12 hours.
- Peak effects are generally experienced between 3 to 6 hours after consumption, followed by a gradual comedown.
Mechanism of Action:
- Like other psychedelic phenethylamines, methallylescaline is believed to exert its effects primarily by acting as a partial agonist at serotonin receptors in the brain, particularly the 5-HT2A receptor. This receptor is associated with the hallucinogenic effects of psychedelics.
Comparison to Mescaline:
- Mescaline is a natural psychedelic that has been used for centuries in indigenous rituals. Methallylescaline is structurally similar but tends to be more potent in terms of dosage (mescaline typically requires doses in the hundreds of milligrams).
- The effects of methallylescaline are often described as brighter or more energetic than mescaline, with a shorter duration.
Risks and Side Effects:
- Nausea and Vomiting: As with many psychedelics, nausea is a common side effect, especially during the onset of the experience.
- Anxiety or Paranoia: Higher doses can lead to feelings of anxiety, confusion, or paranoia, especially in those unaccustomed to strong psychedelics.
- Elevated Heart Rate: Methallylescaline may cause an increase in heart rate and

blood pressure, which can be concerning for individuals with pre-existing cardiovascular conditions.

Tolerance and Cross-Tolerance:
- Like most psychedelics, methallylescaline can lead to rapid tolerance. Repeated use over a short period will result in diminished effects, and a break of several days or more is usually needed to reset tolerance levels.
- Cross-tolerance can also occur with other psychedelics, meaning if you use methallylescaline, substances like LSD, psilocybin, or mescaline may have reduced effects if taken shortly after.
Legal Status:
- Methallylescaline is typically sold as a research chemical, and its legal status varies by country. In many places, it is unscheduled, but it could fall under analog laws due to its similarity to other controlled psychedelics like mescaline.

Conclusion

Methallylescaline is a synthetic psychedelic phenethylamine offering experiences akin to mescaline but with unique properties due to its chemical structure. It remains largely unstudied and should be handled cautiously, keeping harm-reduction practices in mind. Its appeal lies in its ability to produce intense, introspective, and visual experiences, though risks related to its unknown toxicity and legal status should not be ignored.

Additional information

Quantity	1 Gram , 5 Grams , 10 Grams

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