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Pyrazolam is a synthetic benzodiazepine derivative first developed and studied in the 1970s but has since become known as a “research chemical” due to its availability in the recreational and research drug markets. Unlike some benzodiazepines used in medical treatments, pyrazolam is not approved for therapeutic use and is typically sold online for research purposes. It is primarily known for its anxiolytic (anti-anxiety) and sedative properties.

Key Characteristics of Pyrazolam

1. Chemical Structure and Properties:
   • SH-I-04 is structurally related to other benzodiazepines but features a pyrazole ring fused to the traditional benzodiazepine structure, which distinguishes it from other drugs in the same family.
   • It has a high binding affinity for GABA-A receptors, the same neurotransmitter receptor targeted by other benzodiazepines. This binding contributes to its sedative and calming effects.
2. Mechanism of Action:
   • Pyrazolam works by enhancing the activity of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter in the brain. This action decreases neuronal activity, leading to reduced anxiety, sedation, and muscle relaxation.
   • Unlike some benzodiazepines, SH-I-04 has been shown to be a partial agonist at certain GABA-A receptor sites, which may reduce its potential for sedation and impairments in motor coordination at lower doses compared to other benzodiazepines.
3. Effects:
   • Anxiolytic (Anti-Anxiety): Pyrazolam is noted for its strong anti-anxiety effects, which make it popular among users seeking relief from anxiety and panic.
   • Sedation: At higher doses, SH-I-04 can induce drowsiness, though it is generally considered less sedating than other benzodiazepines like diazepam or alprazolam.
   • Muscle Relaxation: Like many benzodiazepines, SH-I-04 can have muscle relaxant properties, though its effects are typically milder in this regard.
   • Cognitive and Motor Impairment: While its partial agonist nature reduces some risks, higher doses of SH-I-04 can still cause impairments in coordination, slowed reflexes, and memory issues.
4. Onset and Duration:
   • Onset of Action: Pyrazolam has a relatively rapid onset, with effects generally felt within 30-60 minutes after oral administration.
   • Duration of Effects: The effects can last from 6 to 10 hours, depending on the dose, though it has a relatively moderate half-life compared to other benzodiazepines.
5. Tolerance and Dependence:
   • Tolerance: Repeated use of SH-I-04 can lead to tolerance, meaning users need higher doses to achieve the same effects. Tolerance to the anxiolytic effects can develop within days or weeks.
   • Dependence: Long-term or high-dose use may result in physical and psychological dependence, similar to other benzodiazepines. Abruptly stopping SH-I-04 can lead to withdrawal symptoms, including anxiety, insomnia, agitation, and, in severe cases, seizures.
6. Legal Status:
   • Research Chemical: SH-I-04 is not approved for medical use in most countries and is primarily sold online as a research chemical, often with disclaimers against human consumption.
   • Controlled Substance: Its legal status varies globally, with some countries placing restrictions due to its similarity to controlled benzodiazepines. In the U.S., it is not a scheduled substance but is subject to regulation under analog acts. In the UK and other European nations, SH-I-04 may be controlled or restricted.
7. Safety and Side Effects:
   • Potential for Overdose: While pyrazolam is less potent than some benzodiazepines, taking high doses or combining it with other depressants (such as alcohol or opioids) can increase the risk of respiratory depression and overdose.
   • Sedation and Cognitive Impairment: At higher doses, users may experience drowsiness, dizziness, memory impairment, and poor coordination, which can make activities like driving dangerous.
   • Withdrawal Symptoms: SH-I-04 can cause withdrawal effects if use is abruptly discontinued, especially after long-term or high-dose usage.
8. Comparison with Other Benzodiazepines:
   • Pyrazolam is often compared to other popular benzodiazepines, such as alprazolam (Xanax) and diazepam (Valium), but is considered less potent in terms of sedation and muscle relaxation. However, it is valued for its relatively strong anti-anxiety effects.
   • Its partial agonist properties may make it somewhat safer in terms of reducing severe sedation or motor impairment at therapeutic doses, but the overall risk profile is similar to other benzodiazepines in terms of dependence and withdrawal.

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What Is Pyrazolam?

Pyrazolam, also known as “pyza,” is a benzodiazepine medicine that is utilized to treat nervousness problems. It’s like different benzodiazepines, like Xanax, and it works by dialing back the action of the cerebrum. Assuming you’re thinking about taking SH-I-04, you should converse with your PCP first. This is because SH-I-04 can be habit-forming and finding the right dose for you is significant. SH-I-04 can likewise cause sluggishness, so you ought to abstain from driving or working large equipment while you’re taking it.

The chemical structure of Pyrazolam is C16H12BrN5. It has a molecular weight of 354.2 g/mol and a molecular formula of C16H12BrN5. SH-I-04 has structural similarities to alprazolam and bromazepam . Its chemical structure can be represented as follows: BrC1=CC(C(C2=CC=CC=N2)=NC3)=C(C=C1)N4C3=NN=C4CBrC1​=CC(C(C2​=CC=CC=N2​)=NC3​)=C(C=C1​)N4​C3​=NN=C4​C

A benzene ring is fused to a diazepine ring, which is a seven membered ring with the two nitrogen elements placed at R1 and R4. At R7, bromine is linked to this bicyclic molecule. Furthermore, the bicylic core is substituted with a 2-pyridine ring at R6.

A 1-methylated triazole ring is fused to and incorporates R1 and R2 of the diazepine ring in pyrazolam. SH-I-04 belongs to a family of benzodiazepines having this fused triazole ring, called triazolobenzodiazepines, identified by the suffix “-zolam”. Can You Buy Research Chemicals And Drugs Online?

SH-I-04 is a potent and fast-acting benzodiazepine that is now available to buy online. Whether you’re looking to order SH-I-04 for personal use or to stock up for your business, [website] is the perfect place to do it. We offer Pyrazolam for sale online, and we ship to customers in the USA, Canada, Germany, Indonesia, Europe, Africa, Israel, Russia, Netherlands, Turkey, Thailand, Japan, and many other countries worldwide.

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Pyrazolam is a Schedule IV drug, which means it has a low potential for abuse and can be prescribed by doctors in certain cases. If you’re interested in trying SH-I-04, make sure you talk to your doctor first to see if it’s the right option for you. and that implies it has a low potential for misuse and can be endorsed by specialists in specific cases. Assuming you’re keen on attempting SH-I-04, ensure you converse with your PCP first to check whether it’s the ideal choice for you.

Summary

Pyrazolam is a benzodiazepine analogue with notable anti-anxiety and sedative effects, popular in research chemical markets. While its effects are milder in some areas compared to other benzodiazepines, it still carries the same risks of dependence, tolerance, and potential for abuse. It is not approved for medical use in most countries, and its legality varies, with some countries regulating it due to its structural and functional similarities to other benzodiazepines.