Buy Picamilon Online | Picamilon Benefits – Cathinone Labs

Picamilon (also known as Pikamilon or nicotinoyl-GABA) is a nootropic compound created by combining niacin (vitamin B3) with GABA (gamma-aminobutyric acid), a neurotransmitter known for its calming effects. It was developed in the Soviet Union in the 1960s to enhance cognitive function and relieve anxiety. Picamilon is unique because it can cross the blood-brain barrier, delivering both niacin and GABA directly to the brain, which many GABA supplements alone cannot do.

Key Features of Picamilon:

Chemical Structure:

• Combination of Niacin and GABA: Picamilon is a synthetic compound formed by binding niacin to GABA. This allows the compound to cross the blood-brain barrier, after which it is broken down into its components in the brain.
• Niacin (Vitamin B3): Niacin is a vasodilator, meaning it widens blood vessels and increases blood flow, particularly to the brain. This can enhance oxygen and nutrient delivery, potentially improving mental clarity.
• GABA: GABA is an inhibitory neurotransmitter that reduces neural activity, promoting a calming effect and reducing feelings of stress and anxiety.

Mechanism of Action:

Once Picamilon crosses the blood-brain barrier, it is hydrolyzed (broken down) into niacin and GABA, both of which have distinct effects:

• GABA: The release of GABA in the brain can produce anxiolytic (anti-anxiety) and calming effects by inhibiting neuronal excitability. This helps to promote relaxation and reduce stress.
• Niacin: The niacin component causes vasodilation, increasing blood flow to the brain. This enhanced cerebral circulation can improve cognitive function, alertness, and focus, making Picamilon helpful for both calming the mind and enhancing mental performance.

Effects:

• Anti-Anxiety: Picamilon is used to reduce anxiety, stress, and nervousness due to the calming effects of GABA. It is considered non-sedative, so it promotes relaxation without causing drowsiness.
• Mood Enhancement: Users often report improvements in mood and a reduction in mental fatigue, making it useful for dealing with mild depression or emotional stress.
• Cognitive Enhancement: Thanks to the niacin component, Picamilon may improve mental clarity, focus, and concentration. This makes it popular as a nootropic for enhancing productivity and mental performance.
• Improved Blood Flow: The vasodilating effect of niacin increases blood flow to the brain, which can help with brain function, particularly in cases of mental fatigue or headaches caused by poor circulation.

Dosage and Duration:

• Dosage: Common dosages of Picamilon range from 50 mg to 300 mg per day, typically taken in divided doses throughout the day. Lower doses (50-100 mg) are usually used for anxiety relief, while higher doses (200-300 mg) are used for cognitive enhancement.
• Duration: The effects of Picamilon can last for about 4 to 6 hours, depending on the dose.

Potential Side Effects:

Picamilon is generally well-tolerated, but some users may experience side effects, especially at higher doses:

• Headaches: Niacin’s vasodilating effect may cause headaches in some users, especially those who are sensitive to increased blood flow.
• Dizziness: Increased circulation and blood pressure changes may lead to dizziness or light-headedness, particularly in higher doses.
• Flushing: Niacin can cause flushing, a temporary reddening and warming of the skin, especially at higher doses. This is a common side effect of niacin itself.
• Nausea or Stomach Discomfort: Some users may experience gastrointestinal discomfort, such as nausea or an upset stomach.

Comparison to Other Nootropics:

• Versus GABA Supplements: Regular GABA supplements generally cannot cross the blood-brain barrier, which limits their effectiveness in calming the brain. Picamilon, by contrast, can deliver GABA to the brain due to its unique structure.
• Versus Phenibut: Phenibut is another GABA derivative used for anxiety relief, but it is often more sedative and can have a higher potential for tolerance and dependence. Picamilon is considered less sedating and generally has fewer risks of dependence.
• Versus Traditional Anxiety Medications: Compared to pharmaceutical anxiolytics like benzodiazepines, Picamilon is seen as a milder alternative with fewer side effects and a lower risk of dependence. However, its effects may also be less potent in severe anxiety cases.

Legal Status:

• United States: In 2015, the FDA determined that Picamilon does not meet the definition of a dietary supplement because it is a synthetic substance and removed it from the market in some cases. However, it is still available for purchase online in the form of research chemicals.
• Other Countries: Picamilon is available over-the-counter or by prescription in some countries, particularly in Russia, where it is used to treat conditions like anxiety, depression, and cognitive decline.

Research and Uses:

• Anxiety and Stress Relief: Picamilon is used for managing anxiety disorders, panic attacks, and stress in a variety of settings.
• Cognitive Enhancement: Some users take Picamilon to improve mental clarity and alertness during tasks that require sustained attention.
• Stroke Recovery and Blood Flow Issues: Picamilon’s vasodilating effects make it potentially useful for people recovering from strokes or suffering from conditions that restrict blood flow to the brain, such as chronic fatigue syndrome or migraine headaches.

Summary:

Picamilon is a nootropic and anxiolytic that combines GABA and niacin to enhance mental clarity while reducing anxiety and stress. Its ability to cross the blood-brain barrier and deliver GABA directly to the brain distinguishes it from standard GABA supplements. Picamilon is well-regarded for being non-sedative, making it suitable for anxiety relief without drowsiness, though side effects like headaches, flushing, and dizziness may occur, especially at higher doses. It has various uses, including cognitive enhancement, mood improvement, and blood flow enhancement, but its availability may be restricted depending on the region.