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2-FPM (2-Fluorophenmetrazine) is a synthetic stimulant that belongs to the phenylmorpholine chemical class. It is closely related to phenmetrazine, a stimulant that was once used medically as an appetite suppressant before being withdrawn due to its potential for abuse. 2-FPM is part of a group of fluorinated amphetamines and phenylmorpholines, and is often sold as a research chemical for its stimulant and nootropic effects.

Key Points About 2-FPM:

Chemical Structure:

• Related to Phenmetrazine: 2-FPM is a fluorinated analog of phenmetrazine, with a fluorine atom attached to the second position of the phenyl ring. This small structural change may affect its potency, duration, and pharmacokinetics compared to phenmetrazine.
• Phenylmorpholine Class: It belongs to the same class of compounds as 3-FPM, which is another fluorinated phenylmorpholine. These substances act as stimulants, similar to amphetamines.

Mechanism of Action:

• Norepinephrine-Dopamine Reuptake Inhibitor (NDRI): 2-FPM primarily acts as a norepinephrine-dopamine reuptake inhibitor, meaning it increases the levels of norepinephrine and dopamine in the brain by blocking their reabsorption. This leads to stimulant effects, such as increased energy, alertness, and focus.
• Milder than Amphetamines: Its effects are often described as more subtle or functional compared to stronger stimulants like amphetamine or methamphetamine. It is considered less euphoric but still stimulating.

Effects:

Users report a range of stimulant effects from 2-FPM, though these can vary based on dosage and individual tolerance:

• Increased Focus and Concentration: One of the primary effects is enhanced mental clarity and sustained focus, which is why it has been used as a nootropic.
• Alertness and Wakefulness: 2-FPM can increase wakefulness and reduce fatigue, making it similar to traditional stimulants used for combating drowsiness or maintaining attention during extended periods of activity.
• Mild Euphoria: Some users report mild euphoria, though this is usually less intense compared to other stimulants like MDMA or amphetamine.
• Stimulation without Overstimulation: It is considered a more “functional” stimulant, providing energy and focus without the intense jitteriness or hyperactivity that can come from other more potent stimulants.

Dosage and Duration:

• Dosage: Common dosages range between 10 to 30 mg, with lower doses used for focus and wakefulness, and higher doses for more pronounced stimulation.
• Onset: The effects generally begin within 30 to 60 minutes after ingestion (when taken orally).
• Duration: The duration of effects typically lasts between 4 to 6 hours, though the comedown or residual effects may persist for several hours afterward.

Potential Risks and Side Effects:

• Cardiovascular Effects: Like other stimulants, 2-FPM can increase heart rate and blood pressure, which may pose risks for individuals with cardiovascular issues.
• Anxiety and Jitters: At higher doses, users may experience anxiety, restlessness, or physical jitteriness, especially if sensitive to stimulants.
• Insomnia: Due to its stimulating effects, taking 2-FPM later in the day can lead to difficulty sleeping.
• Addiction and Dependence: There is a potential for psychological dependence with repeated use, as with many stimulants. While 2-FPM is often described as less addictive than more euphoric stimulants, caution is still advised.

Legal Status:

• Research Chemical: 2-FPM is typically sold as a research chemical, meaning it is not intended for human consumption and occupies a legal gray area in many countries. Its legal status varies, with some regions explicitly banning it or controlling it under analog laws, while in others it may be available for purchase.

Summary:

2-FPM is a mild stimulant and norepinephrine-dopamine reuptake inhibitor that provides mental stimulation, increased focus, and wakefulness. It is generally described as a functional stimulant, used by individuals looking for cognitive enhancement or energy without the more intense side effects associated with stronger stimulants. However, caution is advised due to its potential cardiovascular effects and the risk of addiction, as well as its unclear legal status in many areas.