4B-MAR
$110.00 – $2,500.00
4B-MAR, or 4-Bromo-4-methylaminorex, is a synthetic stimulant that belongs to the aminorex family, similar to other aminorex derivatives such as 4-methylaminorex (4-MAR) and 4-chloro-4-methylaminorex (4C-MAR). The compound is a modified version of aminorex, distinguished by the addition of a bromine atom at the 4-position on its molecular structure. This small change can affect the potency, duration, and psychoactive effects of the compound.
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4B-MAR, or 4-Bromo-4-methylaminorex, is a synthetic stimulant that belongs to the aminorex family, similar to other aminorex derivatives such as 4-methylaminorex (4-MAR) and 4-chloro-4-methylaminorex (4C-MAR). The compound is a modified version of aminorex, distinguished by the addition of a bromine atom at the 4-position on its molecular structure. This small change can affect the potency, duration, and psychoactive effects of the compound.
Chemical Structure and Composition
- Chemical Formula: The chemical structure of 4B-MAR is a modification of aminorex with a bromo substitution at the 4-position.
- Related Compounds: It is structurally related to other stimulants and derivatives in the aminorex family, including 4-MAR, which is known for its stimulant properties similar to amphetamines. The bromo group differentiates 4B-MAR from other aminorex analogues.
Mechanism of Action
- Stimulant Properties: 4B-MAR, like other aminorex derivatives, is thought to work by affecting dopamine and norepinephrine pathways in the brain, leading to heightened arousal, energy, and potential euphoria. It likely acts by increasing the release of these neurotransmitters, creating effects similar to amphetamine-based stimulants.
- Central Nervous System (CNS) Stimulant: The compound has stimulant effects that influence the central nervous system, leading to increased alertness, wakefulness, and reduced appetite.
Effects and Usage
While research on 4B-MAR is limited, the effects can be inferred based on its relation to other aminorex compounds:
- Euphoria and Energy: Users may experience feelings of euphoria, increased energy, and alertness.
- Focus and Concentration: Some stimulants in this class are reported to enhance focus, though often with potential over-stimulation.
- Physical Stimulation: Increased heart rate, higher blood pressure, and a stimulated state similar to amphetamines are common.
Side Effects and Risks
Due to its stimulant properties, 4B-MAR carries significant risks:
- Cardiovascular Strain: Like other stimulants, 4B-MAR can increase heart rate and blood pressure, putting strain on the cardiovascular system.
- Mental Health Risks: High doses or prolonged use could lead to anxiety, paranoia, and even psychosis, similar to other stimulants.
- Addiction Potential: Due to its impact on dopamine pathways, there is a risk of dependence and addiction.
- Limited Research: With limited formal studies, the full range of effects and potential risks remains largely unknown, contributing to unpredictable side effects.
Legal Status
- Controlled Substance: Many aminorex derivatives are controlled substances in multiple jurisdictions due to their psychoactive properties and health risks. 4B-MAR’s legal status may vary, but it is often classified alongside other synthetic stimulants, making it potentially illegal in many regions.
4-Methylaminorex (4-MAR, 4-MAX) is a stimulant drug of the 2-amino-5-aryloxazoline class, first synthesized in 1960 by McNeil Laboratories. It is also known by its street name “U4Euh” or “Euphoria”. Due to its potential for abuse, 4-methylaminorex is banned in many countries as a stimulant.
Pharmacology
4-Methylaminorex has effects comparable to those of amphetamine or cathinone, a methyl derivative synthesized as early as 1960. It is a central stimulant, and its bioavailability varies depending on the route of administration: 62% oral, 79% nasal, 91-93.5% smoked, and 100% IV. It is metabolized hepatically and eliminated with a half-life of 10-19 hours, primarily through renal excretion.
Legal Status
4-Methylaminorex has a restricted legal status worldwide. According to the search results, it is:
- Schedule III in Canada
- Anlage I (Authorized scientific use only) in Germany
- Class A in the UK
- Schedule I in the US
- Prohibited substance in Australia and Brazil
Synthetic Derivatives
Recently, three halogenated derivatives of 4-methylaminorex have been developed as substitution products: 4′-fluoro-4-methylaminorex (4F-MAR), 4′-chloro-4-methylaminorex (4C-MAR), and 4′-bromo-4-methylaminorex (4B-MAR). These derivatives have been characterized using various analytical techniques, including NMR spectroscopy, LC-HRMS, and chiral HPLC-UV.
Recreational Use
4-Methylaminorex and its derivatives have been detected in various online shops and have appeared on the illicit market. The drug has been associated with recreational use, particularly in Europe. However, its use has been linked to severe health consequences, including pulmonary hypertension.
Conclusion
4B-MAR (4-Bromo-4-methylaminorex) is a synthetic stimulant in the aminorex family, notable for its stimulant and potentially euphoric effects. While similar to other stimulants, it carries health risks like cardiovascular strain, mental health issues, and dependency potential. Its limited research and likely controlled status in many regions make it a high-risk compound for unregulated use.
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